It ran for five seasons on CBS. The words, "Unca Bill, Unca Bill" were heard weekly. The show is called Family Affair, and it began its run this day in 1966 on CBS. The series starred movie star Brian Keith along with Sebastian Cabot, and the three waifs in his ward - Johnny Whitaker, Anissa Jones, and Cathy Garver. Nancy Walker became a regular in later seasons. A piece of the debut episode can be seen below.